Two new phenolic compounds from the leaves of Alnus sibirica Fisch. ex Turcz.

نویسندگان

  • Manh Heun Kim
  • Kwan Hee Park
  • So Ra Kim
  • Kwang Jun Park
  • Myeong Hwan Oh
  • Jun Hyeok Heo
  • Ki Hoon Yoon
  • Jun Yin
  • Kyu Hyung Yoon
  • Min Won Lee
چکیده

Two new phenolic compounds, 4-O-glucopyranosyl-5-O-caffeoylshikimic acid (1) and 2,3-digalloyl oregonin (2), were isolated along with eight known phenolic compounds (3-10) from an 80% acetone extract of Alnus sibirica leaves. The chemical structures of these compounds were elucidated using 1D/2D nuclear magnetic resonance and high resolution-MS. The anti-oxidative activities of these compounds were determined by assaying their 1,1-diphenyl-2-picrylhydrazyl radical and nitroblue tetrazolium superoxide anion scavenging activity. All of the isolated phenolic compounds (1-10) exhibited potent anti-oxidative activities. In particular, 2 and 4, which are diarylheptanoids, and 10 which is ellagitannin exhibited excellent anti-oxidative activities with almost the same potency as that of the positive controls L-ascorbic acid and allopurinol.

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عنوان ژورنال:

دوره 30  شماره 

صفحات  -

تاریخ انتشار 2016